Introduction to General, Organic, and Biochemistry, 12th Edition

Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres

Copyright 2020
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Introduction to General, Organic, and Biochemistry 12th Edition by Frederick A. Bettelheim/William H. Brown/Mary K. Campbell/Shawn O. Farrell/Omar Torres

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Overview
Meet the Authors
What's New
Features
Table of Contents
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Overview

This bestselling text provides health science students with a strong focus on current issues, a pedagogically rich framework, a wide variety of medical and biological applications, a visually dynamic art program, and exceptionally strong and varied practice and end-of-chapter problems. Revised and updated throughout, this edition now includes new content, new and updated Chemical Connections, new and revised problems, and more. Most end-of-chapter problems are available in the OWLv2 online learning solution.

Meet the Authors

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Frederick A. Bettelheim

Frederick Bettelheim was a distinguished university research professor at Adelphi University and a visiting scientist at the National Eye Institute. He co-authored seven editions of INTRODUCTION TO GENERAL, ORGANIC, AND BIOCHEMISTRY, ORGANIC CHEMISTRY, and several Laboratory Manuals. He is also the author of EXPERIMENTAL PHYSICAL CHEMISTRY and co-author of numerous monographs and research articles. Professor Bettelheim received his Ph.D. from the University of California, Davis.

William H. Brown

William H. Brown is emeritus professor of chemistry at Beloit College, where he was twice named Teacher of the Year. His teaching responsibilities include organic chemistry, advanced organic chemistry and, more recently, special topics in pharmacology and drug synthesis. He received his Ph.D. from Columbia University under the direction of Gilbert Stork and did postdoctoral work at California Institute of Technology and the University of Arizona.

Mary K. Campbell

Mary K. Campbell was Professor Emeritus of chemistry at Mount Holyoke College, where she taught biochemistry, general chemistry, and physical chemistry, as well as advised undergraduates working on biochemical research projects. Her avid interest in writing led to the publication of many highly successful editions of INTRODUCTION TO GENERAL, ORGANIC, AND BIOCHEMISTRY. She also coauthored BIOCHEMISTRY with Shawn O. Farrell. Originally from Philadelphia, Dr. Campbell received her Ph.D. from Indiana University and completed post-doctoral work in biophysical chemistry at Johns Hopkins University. Her areas of interest included researching the physical chemistry of biomolecules, specifically, spectroscopic studies of protein-nucleic acid interactions.

Shawn O. Farrell

Shawn O. Farrell, a native of Northern California, received his B.S. in biochemistry from University of California, Davis, studying carbohydrate metabolism. He completed his Ph.D. in biochemistry at Michigan State University, where he focused on the study of fatty acid metabolism. Dr. Farrell became interested in biochemistry while in college, as it was relevant to his passion for bicycle racing. He raced competitively for 15 years and now officiates bicycle races worldwide. He has taught biochemistry lecture and laboratory courses at Colorado State University for 16 years and now works for USCycling. Professor Farrell has written scientific journal articles about specific research projects and about laboratory teaching, as well as articles for sports publications, such as "Salmon, Trout, and Steelheader" magazine. He is co-author with Mary Campbell on BIOCHEMISTRY, 7e (Cengage Learning).

Omar Torres

Omar Torres received his undergraduate degree in Chemistry from Texas A&M University in 1998 and his graduate degree in Inorganic Chemistry from UCLA in 2001. He has experience in teaching, research (inorganic, organic, and analytical) and academic administration. Professor Torres taught both inorganic and organic chemistry at UCLA, where he earned two UCLA Department of Chemistry Awards for Excellence in Teaching for the 1998-1999 and 1999-2000 school years. In addition, Professor Torres has worked at the Dow Chemical Company (Freeport, TX) in the area of Analytical Quality Control, developing and implementing new technologies for various plant operators and analytical scientists. He is currently Dean of Science at the College of the Canyons.

What's New

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Chemical Connections: More than 150 essays with photos--many new or updated for the 12th Edition--describe applications of chemical concepts presented in the text, linking the chemistry to their real uses.
More accessible content: Chapter 12 now combines the chapter on Alkenes and Alkanes with the chapter on Benzenes and Its Derivatives to make the material easier to master.
Expanded coverage: For example, the list of common organic functional groups now includes amides and presents a schematic of a tripeptide to show the importance of amide bonds in the structure of polypeptides and proteins; the discussion of the reactions of phenols now includes the oxidation of phenols to quinones and the use of the hydroquinone to quinone interconversion in black-and-white photography; the role of Coenzyme Q (ubiquinone) in the respiratory chain as a carrier of electrons; and the structure of vitamin K and its role in blood clotting.
An increased number of practice problems per chapter: Chapters 21-31 now have at least one example problem with answer, followed by a Quick Check problem where the answer is not worked out.
New sections: Content has been updated throughout to reflect advances in the field and material of particular importance to students.
Enhanced OWLv2 Course: The new edition of the text features a more powerful OWLv2 course with hints and answer-specific feedback for select end-of-chapter questions, math remediation, and laddered assessments.

Features

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Problem-Solving Strategies: To help students organize the information to solve a problem, each chapter example includes a description of the strategy used to arrive at the solution.
Visual Impact: Many illustrations increase pedagogical impact. Figures such as Figures 6.4 (Henry’s Law) and 6.11 (electrolytic conductance) show the microscopic and macroscopic aspects of a topic under discussion.
Chapter Summaries: At the end of each chapter, restated key questions are followed by summary paragraphs that highlight the concepts associated with the questions.
"How To" Boxes: Emphasizing the skills students need to master the material, "How To" boxes cover such topics as "How to Determine the Number of Significant Figures in a Number" (Chapter 2) and "How to Interpret the Value of the Equilibrium Constant, K" (Chapter 7).

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1. Matter, Energy, and Measurement.
2. Atoms.
3. Chemical Bonds.
4. Chemical Reactions.
5. Gases, Liquids, and Solids.
6. Solutions and Colloids.
7. Reaction Rates and Chemical Equilibrium.
8. Acids and Bases.
9. Nuclear Chemistry.
10. Organic Chemistry.
11. Alkanes.
12. Alkenes, Alkynes, and Aromatic Compounds
13. Alcohols, Ethers, and Thiols.
14. Chirality: The Handedness of Molecules.
15. Amines.
16. Aldehydes and Ketones.
17. Carboxylic Acids.
18. Carboxylic Anhydrides, Esters, and Amides.
19. Carbohydrates.
20. Lipids.
21. Proteins.
22. Enzymes.
23. Chemical Communications: Neurotransmitters and Hormones.
24. Nucleotides, Nucleic Acids, and Heredity.
25. Gene Expression and Protein Synthesis.
26. Bioenergetics: How the Body Converts Food to Energy.
27. Specific Catabolic Pathways: Carbohydrate, Lipid, and Protein Metabolism.
28. Biosynthetic Pathways.
29. Nutrition.
30. Immunochemistry
31. Body Fluids.
Appendix 1. Exponential Notation.
Appendix 2. Significant Figures.
Answers to In-Text and Odd-Numbered End-of-Chapter Problems.
Glossary
Credits
Index.